Sertraline (Common Indian Brands: Zosert, Daxid, Serlift)

Introduction
Sertraline is a widely prescribed antidepressant used to treat depression and anxiety-related disorders. It belongs to the class of Selective Serotonin Reuptake Inhibitors (SSRIs), which work by increasing the levels of serotonin in the brain, helping to enhance mood and reduce anxiety. Sertraline is effective in restoring emotional balance and improving overall well-being.

Purpose of the Medication
Used to Treat:

Major Depressive Disorder (MDD)
Generalized Anxiety Disorder (GAD)
Obsessive-Compulsive Disorder (OCD)
Panic Disorder
Post-Traumatic Stress Disorder (PTSD)
Social Anxiety Disorder (SAD)
How It Works:

Boosts serotonin levels in the brain by inhibiting its reuptake, which helps regulate mood and reduce symptoms of anxiety and depression.
Key Information
How to Take It:

Common starting dose:
Adults: 25–50 mg once daily.
Children (OCD): 25 mg daily (increased gradually).
Maximum dose: 200 mg/day.
Take at the same time daily, preferably in the morning or evening.
Can be taken with or without food.
Swallow the tablet whole with water; do not crush or chew.
Common Side Effects:

Nausea
Diarrhea
Dry mouth
Sleep disturbances (insomnia or drowsiness)
Dizziness
Increased sweating
Serious Side Effects:

Seek medical attention immediately if you experience:
Thoughts of self-harm or suicide.
Severe agitation, confusion, or hallucinations.
Symptoms of serotonin syndrome (e.g., rapid heartbeat, fever, muscle stiffness).
Allergic reactions (rash, swelling, difficulty breathing).
Precautions
Before Taking: Inform your doctor if you have:

A history of seizures or epilepsy.
Bipolar disorder or a history of manic episodes.
Liver or kidney problems.
Any bleeding disorders or if you take blood-thinners.
Pregnancy, breastfeeding, or plan to conceive.
Any allergies or if you use Ayurvedic, herbal, or homeopathic supplements.
While Taking:

Avoid alcohol, as it can worsen dizziness or drowsiness.
Be cautious while driving or operating machinery until you know how sertraline affects you.
Regularly monitor for any unusual changes in mood or behavior.
Storage
Store at room temperature in a cool, dry place away from moisture and sunlight.
Keep out of reach of children and pets.
Missed Dose
Take it as soon as you remember unless it’s close to the next scheduled dose.
Do not double the dose to compensate for a missed one.
Interactions
Medicines to Avoid Without Doctor’s Advice:

Other antidepressants, especially monoamine oxidase inhibitors (MAOIs).
Blood-thinners (e.g., warfarin) and non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or aspirin (increased bleeding risk).
Herbal supplements like St. John’s Wort (risk of serotonin syndrome).
Always inform your doctor about all medications, including traditional and alternative therapies, you are taking.

Emergency Contact
Overdose Symptoms: Severe dizziness, irregular heartbeat, fainting, seizures, or vomiting.

Contact the Poison Information Centre, AIIMS New Delhi, at 011-26589391 or visit the nearest emergency room immediately.
Additional Notes
Brands Available in India:

Zosert (Sun Pharma): 25 mg, 50 mg, 100 mg tablets.

Daxid (Pfizer): 25 mg, 50 mg, 100 mg tablets.

Serlift (Cipla): 25 mg, 50 mg tablets.

It may take 1–4 weeks to feel the full effect of the medication.

Avoid abrupt discontinuation to prevent withdrawal symptoms like mood changes, irritability, or flu-like symptoms.

Regular follow-ups with your doctor are essential to monitor your progress and adjust the dose as necessary.