Quetiapine (Common Indian Brands: Qutipin, Seroquin, Quitipin)

Introduction
Quetiapine is an atypical antipsychotic medication commonly prescribed to treat mental health conditions such as schizophrenia, bipolar disorder, and depression (as part of a combination therapy). It works by balancing the activity of neurotransmitters like dopamine and serotonin in the brain, helping to alleviate symptoms such as mood swings, psychosis, and anxiety.

Purpose of the Medication
Used to Treat:

Schizophrenia
Bipolar Disorder (manic and depressive episodes)
Major Depressive Disorder (MDD) as adjunct therapy
Generalized Anxiety Disorder (off-label in some cases)
How It Works:

Modulates dopamine D2 and serotonin 5-HT2A receptors to stabilize mood, reduce psychotic symptoms, and improve emotional balance.
Key Information
How to Take It:

Common starting dose:
Schizophrenia: 50–100 mg/day, increased gradually.
Bipolar Disorder (mania): 100–200 mg/day, titrated to 400–800 mg/day.
Depression (adjunct): 50 mg/day, up to 300 mg/day as prescribed.
Maximum dose: 800 mg/day (as advised by your doctor).
Can be taken with or without food, usually once daily at bedtime or as divided doses.
Swallow tablets whole; do not crush or chew.
Common Side Effects:

Drowsiness or sedation
Dry mouth
Dizziness
Weight gain
Constipation
Increased appetite
Serious Side Effects:

Seek immediate medical help if you experience:
Severe drowsiness or confusion.
Symptoms of Neuroleptic Malignant Syndrome (e.g., fever, muscle stiffness, confusion).
Severe allergic reaction (e.g., rash, difficulty breathing, swelling).
High blood sugar symptoms (e.g., excessive thirst, frequent urination).
Precautions
Before Taking: Inform your doctor if you have:

A history of diabetes or risk factors for high blood sugar.
Cardiovascular problems or risk factors like high blood pressure.
A history of seizures, epilepsy, or neurological disorders.
Liver or kidney impairment.
Pregnancy, planning pregnancy, or breastfeeding.
Any allergies or if you use Ayurvedic, herbal, or homeopathic supplements.
While Taking:

Avoid alcohol, as it may worsen drowsiness or dizziness.
Be cautious when driving or operating machinery due to potential sedation.
Monitor weight, blood pressure, and blood sugar levels regularly.
Storage
Store at room temperature in a cool, dry place, away from direct sunlight and moisture.
Keep out of reach of children and pets.
Missed Dose
Take it as soon as you remember unless it’s close to your next scheduled dose.
Do not double the dose to make up for a missed one.
Interactions
Medicines to Avoid Without Doctor’s Advice:

Other antipsychotics or sedatives (e.g., benzodiazepines) may increase drowsiness.
Painkillers like ibuprofen or aspirin (increased bleeding risk).
Medications that prolong the QT interval (e.g., certain antibiotics or heart medications).
Herbal supplements like St. John’s Wort.
Always inform your doctor about all medications you’re taking, including traditional and alternative therapies.

Emergency Contact
Overdose Symptoms: Severe drowsiness, fainting, confusion, or irregular heartbeat.

Contact the Poison Information Centre, AIIMS New Delhi, at 011-26589391 or visit the nearest emergency room immediately.
Additional Notes
Brands Available in India:

Qutipin (Sun Pharma): 25 mg, 50 mg, 100 mg, 200 mg tablets.

Seroquin (Lupin): 25 mg, 100 mg, 200 mg tablets.

Quitipin (Torrent): 25 mg, 50 mg, 100 mg, 300 mg, 400 mg tablets.

It may take 1–2 weeks for noticeable symptom relief and several weeks for full therapeutic effects.

Do not stop the medication abruptly without consulting your doctor, as this may cause withdrawal symptoms such as anxiety or insomnia.

Regular follow-ups with your doctor are essential to monitor side effects and adjust your dosage.